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Indication & Dosage |
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| Intramuscular |
| PROVISION OF MUSCLE RELAXATION IN GENERAL ANESTH INCLUDING ENDOTRACHEAL INTUBATION, ENDOSCOPY AND ELECTROCONVULSIVE THERAPY |
| Child:
As chloride: single dose of 0.3-1.1 mg/kg injected; supplementary doses of 50-100% of the initial dose may be given at 5-10 min intervals. Max dose (repeated IV injection or continuous infusion): 500 mg/hr |
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| Intramuscular |
| PROVISION OF MUSCLE RELAXATION IN GENERAL ANESTH INCLUDING ENDOTRACHEAL INTUBATION, ENDOSCOPY AND ELECTROCONVULSIVE THERAPY |
| Adult:
As chloride: single dose of 0.3-1.1 mg/kg injected; supplementary doses of 50-100% of the initial dose may be given at 5-10 min intervals. Max dose (repeated IV injection or continuous infusion): 500 mg/hr |
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| Intravenous |
| PROVISION OF MUSCLE RELAXATION IN GENERAL ANESTH INCLUDING ENDOTRACHEAL INTUBATION, ENDOSCOPY AND ELECTROCONVULSIVE THERAPY |
| Child:
As chloride: <1 yr: 2 mg/kg; 1-12 yr: 1 mg/kg. |
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| Intravenous |
| PROVISION OF MUSCLE RELAXATION IN GENERAL ANESTH INCLUDING ENDOTRACHEAL INTUBATION, ENDOSCOPY AND ELECTROCONVULSIVE THERAPY |
| Adult:
As chloride: single dose of 0.3-1.1 mg/kg injected; supplementary doses of 50-100% of the initial dose may be given at 5-10 min intervals. Max dose (repeated IV injection or continuous infusion): 500 mg/hr |
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| Precautions |
Bone fracture, raised intraocular pressure, neuromuscular disease, infants, childn, adolescents, pregnancy and lactation. |
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Potentially Life-threatening
Adverse Drug Reactions |
Bradycardia, tachycardia, hypotension, hyperpertension, raised intraocular pressure, hyperkalaemia, excessive salivation. |
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| Adverse Drug Reactions |
Respiratory depression, dysrhythmias, rhabdomyolsis, malignant hyperthermia. |
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| Interactions |
Concurrent use with anticholinesterases, cyclophosphamide, antiarrhythmics, aminoglycosides, lincosamides (clindamycin and lincomycin), anticonvulsants, phenelzine, magnesium, metoclopramide, inhalation anaesthetics, exposure to organophosphate insecticides may enhance neuromuscular block of suxamethonium. Increased risk of arrhythmias with cardiac glycosides. |
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